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Effect of Nutritional Supplementation With Turmeric on the Cognitive Performance of Subjects With Metabolic Syndrome

NCT04705220 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 85

Last updated 2026-02-02

No results posted yet for this study

Summary

The EPICURO study aims to demonstrate the beneficial effects of a 6-month dietary supplementation with an improved bioavailable turmeric (MERIVA®) on inflammatory, oxidative and metabolic parameters together with cognitive performance, potentially resulting in the reduction of the risk of cognitive decline in subjects, male and female, with Metabolic Syndrome. The results obtained will provide novel insights on MERIVA® for improving the prevention of age-related cognitive decline and Alzheimer's disease.

Conditions

Interventions

DIETARY_SUPPLEMENT

MERIVA® Tablets

The treatment corresponds to 1 g / day of experimental product (corresponding to about 200 mg of curcuminoids).

OTHER

Placebo Tablets

The composition of placebo includes the same components of the treatment tablets, except for the active substance.

Sponsors & Collaborators

  • Istituto Superiore di Sanità

    collaborator OTHER

  • Sintesi Research Srl

    collaborator INDUSTRY

  • Indena S.p.A

    lead INDUSTRY

Principal Investigators

  • Andrea Giaccari, Prof. · Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-08
Primary Completion
2025-10-16
Completion
2025-12-19

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04705220 on ClinicalTrials.gov