TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 Monotherapy
NCT04695327 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2026-03-06
Summary
This is an open-label, phase 1, dose-escalation, multicenter trial evaluating the safety of oncolytic adenovirus TILT-123 as monotherapy in advanced solid tumor patients.
Conditions
Interventions
- BIOLOGICAL
-
TILT-123
TNFalpha and IL-2 coding oncolytic adenovirus TILT-123
Sponsors & Collaborators
-
TILT Biotherapeutics Ltd.
lead INDUSTRY
Principal Investigators
-
Katriina Peltola, MD, PhD · Helsinki University Central Hospital
-
Tuomo Alanko, MD, PhD · Docrates Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-01-11
- Primary Completion
- 2025-09-03
- Completion
- 2025-09-03
Countries
- Finland
Study Locations
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