Interleukin-12 Gene Therapy in Treating Patients With Skin Metastases
NCT00028652 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2019-12-13
Summary
RATIONALE: Inserting the gene for interleukin-12 into a person's skin tumor cells may make the body build an immune response to kill tumor cells.
PURPOSE: Phase I trial to study the effectiveness of interleukin-12 gene therapy in treating patients who have skin metastases.
Conditions
Interventions
- BIOLOGICAL
-
interleukin-12 gene
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
David M. Mahvi, MD · University of Wisconsin, Madison
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-01-31
Countries
- United States
Study Locations
More Related Trials
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma That Has Not Responded to Previous Treatment
NCT00022438 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Plus Interleukin-2 With or Without Interferon Alfa-2b in Treating Patients With Stage III Melanoma
NCT00004104 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00006113 ·Status: TERMINATED ·Phase: PHASE2
-
Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00002845 ·Status: UNKNOWN ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019487 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019721 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00091338 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Stage IV Melanoma
NCT00126685 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Stage III or Stage IV Melanoma
NCT00004025 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Stage IV or Recurrent Melanoma
NCT00012064 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma
NCT00006385 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00054535 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccination With Autologous, Lethally Irradiated Melanoma Cells Engineered by Adenoviral Mediated Gene Transfer to Secrete Granulocyte-Macrophage Stimulating Factor (GMSF)
NCT00809588 ·Status: COMPLETED ·Phase: PHASE1
-
Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00085462 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With gp100 and/or Sargramostim in Treating Patients With Malignant Melanoma
NCT00003897 ·Status: COMPLETED ·Phase: PHASE1
-
Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma
NCT00026143 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-2 and Sargramostim After Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00085579 ·Status: WITHDRAWN ·Phase: PHASE2
-
Cell Therapy for Metastatic Melanoma Using CD8 Enriched Tumor Infiltrating Lymphocytes
NCT01236573 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Biological Therapy in Treating Patients With Metastatic Melanoma
NCT00002786 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Biological Therapy in Treating Patients With Metastatic Melanoma
NCT00045357 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of pIL-12 Electroporation Malignant Melanoma
NCT01502293 ·Status: COMPLETED ·Phase: PHASE2
-
Trial for the Evaluation of the Effect of Systemic Low-dose Interleukin-2 (IL-2) on the Immunogenicity of a Vaccine Comprising Synthetic Melanoma Peptides Administered With Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)-In-Adjuvant, in Patients With High Risk Melanoma
NCT00928902 ·Status: COMPLETED ·Phase: PHASE2
-
Hu14.18-Interleukin-2 Fusion Protein in Treating Patients With Advanced Melanoma
NCT00109863 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Recombinant Interleukin-12 Followed by Daclizumab in Treating Patients With Metastatic Melanoma
NCT01307618 ·Status: TERMINATED ·Phase: PHASE2
-
Gene Therapy in Treating Women With Metastatic Breast Cancer
NCT00849459 ·Status: COMPLETED ·Phase: PHASE1