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Effect of Metoclopramide Versus Erythromycin on on Gastric Residual Volume

NCT04682691 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-01-14

No results posted yet for this study

Summary

In emergencies, it may be necessary to anaesthetize who are not fully starved and consequently at risk of pulmonary aspiration. Pregnancy are recognized to be at increased risk of aspiration compared with non-pregnancy. Prokinetic agents such as metoclopramide can be used to reduce GRV. Metoclopramide is widely used as a prokinetic agent in adults and is licensed for premedication in pregnancy, but its use may be limited by its potential for producing extrapyramidal side effects. Erythromycin is an effective prokinetic agent in adults but there is no work examining its use for premedication in pregnancy. This study compared the effects of erythromycin and metoclopramide on GRV in full-term pregnant women

Conditions

  • Gastric Residual Volume

Interventions

DRUG

Erythromycin (400mg)

oral Erythromycin (400mg)

DRUG

metoclopramide (10mg)

oral metoclopramide (10mg)

DIETARY_SUPPLEMENT

naturally flavored water

naturally flavored water

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Amr wahdan, MD · Cairo university , Cairo, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2024-02-05
Completion
2024-02-22

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04682691 on ClinicalTrials.gov