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Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma

NCT04663880 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27

Last updated 2020-12-11

No results posted yet for this study

Summary

This is a randomized, double blind, cross-over study designed to determine the concentration of airborne house dust mite allergen inducing bronchial response in asthmatic subjects allergic to mite, during allergen exposures in the Alyatec environmental exposure chamber (EEC).

The study was also designed to validate the specificity of the asthmatic reaction induced by exposure to airborne house dust mite allergen in Alyatec EEC.

Conditions

  • Allergic Asthma
  • Allergy to House Dust
  • Allergy

Interventions

OTHER

Exposure to placebo in EEC

Patients are exposed to placebo (saline solution) in the EEC for 4h maximum

OTHER

Exposure to three concentrations of HDM allergen in EEC

Patients are exposed to different concentrations of airborne HDM allergen (Der p1) in the EEC for 4h maximum

OTHER

Exposure to a single concentration of HDM allergen in EEC

Patients are exposed to a single concentration of airborne HDM allergen (Der p1) in the EEC for 4h maximum

Sponsors & Collaborators

  • Alyatec

    lead INDUSTRY

Principal Investigators

  • Frédéric de Blay, Pr. · Alyatec

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-08-30
Primary Completion
2017-01-23
Completion
2017-02-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04663880 on ClinicalTrials.gov