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The Status of Parathyroid Hormone Secretion in Covid-19 Patients

NCT04662437 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2020-12-10

No results posted yet for this study

Summary

COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation in various organs of the body, especially through cytokines in the lungs. This cytokine-mediated widespread inflammation can also affect the parathyroid glands, resulting in impaired parathyroid secretion.

Researchers evaluated the levels of parathyroid hormone, calcium, phosphorus, and alkaline phosphatase in patients hospitalized for COVID-19 infection. Researchers excluded patients on intensive care therapy and patients with known parathyroid disease.

The researchers examined the association of parathyroid hormone secretion with COVID-19 disease, white blood cells, neutrophil / lymphocyte ratio, C reactive protein, fibrinogen, procalcitonin, ferritin, and D-dimer in these patients. The researchers compared the parathyroid hormone level of healthy people without COVID-19 infection and known parathyroid disease with the parathyroid hormone level of Covid-19 patients.

Conditions

  • COVID-19 Infection
  • Parathyroid Gland
  • Parathyroid Hormone
  • Calcium
  • Phosphorus
  • Alkaline Phosphatase

Interventions

DIAGNOSTIC_TEST

Venous blood was collected for biochemistry testing

From the people in the healthy control group, 10 ml of venous blood was collected from the venous vein in the forearm of all individuals in the study. Parathyroid hormone, calcium, phosphorus, alkaline phosphatase levels were measured from this blood.

Sponsors & Collaborators

  • Didem Ertorul

    collaborator UNKNOWN

  • Bezmialem Vakif University

    lead OTHER

Principal Investigators

  • Derya Özalp Çelikçi, Dr · Sancaktepe Education and Research Hospital

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-09-10
Primary Completion
2020-12-01
Completion
2020-12-09

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04662437 on ClinicalTrials.gov