Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV

Summary

The overall goal of this pilot randomized-controlled trial (RCT) is to pilot MASI (MAsakhane Siphucule Impilo Yethu; Xhosa for "Let's empower each other and improve our health"), an ART adherence-supporting smartphone app with 50 adolescents and young adults living with HIV to assess its feasibility and acceptability and to explore preliminary effects on ART adherence and social support.

Conditions

• HIV Infections
• Adolescent Behavior

Interventions

BEHAVIORAL

Social Support

The app will provide opportunities for participants to interact with each other as well as trained peer mentors to receive and provide social support.

BEHAVIORAL

Informational Resources

The app will provide opportunities for participants to review HIV-related health information in engaging formats (e.g., activities, multi-media resources, and answer to users' health questions)

BEHAVIORAL

Self-Monitoring and habit formation

The app will provide opportunities for participants to track their treatment adherence and schedule tailored reminders.

BEHAVIORAL

Goal setting and action planning

The app will provide opportunities for participants to identify goals, select action items, and receive tailored feedback on the action plan.

Sponsors & Collaborators

• University of Cape Town

  collaborator OTHER

• University of North Carolina

  collaborator OTHER

• National Institute of Mental Health (NIMH)

  collaborator NIH

• Florida State University

  collaborator OTHER

• Duke University

  lead OTHER

Principal Investigators

• Marta I Mulawa, PhD · Duke University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

15 Years

Max Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-06-21

Primary Completion

2024-03-15

Completion

2024-04-02

Countries

• South Africa

Study Locations