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The Efficacy of Nifedipine in the Management of Preterm Labor

NCT04644354 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 444

Last updated 2020-11-25

No results posted yet for this study

Summary

Preterm labor is one of the problems of obstetrics, and is one of the leading cause of neonatal morbidity and mortality. The incidence of preterm birth is around 7 to 9 %. The preterm baby is prone to respiratory, renal, neurologic and gastrointestinal problems. The correct diagnosis should be followed by the early administration of the most effective tocolytic agent with least side effects for both mother and fetus. Nifedipine, a calcium channel blocker, has gained a world-wide popularity recently since it has the least side-effects on both mother and fetus. In the present study, we aimed to evaluate the success rate of tocolytic agent 'nifedipine' on the spontaneous preterm labor of singeton pregnant women with intact amnionic membrane.

Conditions

  • Preterm Labor
  • Preterm Birth
  • Preterm Labor Without Delivery
  • Preterm Labor With Preterm Delivery in Third Trimester
  • Calcium-Channel Blockers Toxicity
  • Side Effect of Drug

Interventions

DRUG

Nifedipine 10 mg

For both groups, when preterm labor is diagnosed, 10 mg capsule will be given sublinguially and if it is not effective in 1 hour, the same dose will be repeated again, and the same regimen will be repeated every day till preterm labor ends or proceed to a preterm birth.

Sponsors & Collaborators

  • Ethem Unal, M.D., PhD, Associate Prof of Surgery & Surgic

    lead OTHER_GOV

Principal Investigators

  • Aysun Firat, M.D., Specialist of Obstetrics&Gynecology, Dir · Study Director

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-15
Primary Completion
2020-12-20
Completion
2020-12-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04644354 on ClinicalTrials.gov