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Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate

NCT02337881 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 227

Last updated 2016-06-22

No results posted yet for this study

Summary

The aim of this study is to assess whether or not the emergency tocolytic effect of combined nifedipine and sildenafil citrate will have a superior effect over nifedipine alone in terms of inhibiting eminent preterm labor and improving perinatal outcomes.

Conditions

  • Labor Preterm Requiring Hospitalization

Interventions

DRUG

nifedipen

The protocol for nifedipen in our units consists of 20 mg orally stat, followed by 10 mg orally every 6-8 hours for 48 to 72 hours as needed

DRUG

Sildenafil

sildenafil citrate will be administered vaginally in a dose of 25mg at 8 hourly intervals and both medications will be continued for 48-72 hours as indicated.

Sponsors & Collaborators

  • Menoufia University

    collaborator OTHER

  • Al Hayat National Hospital

    lead OTHER

Principal Investigators

  • menoufia university · menoufia fuculty of medicine

  • Alhayah national hospital · Alhayah national hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2016-10-31
Completion
2016-10-31

Countries

  • Egypt
  • Saudi Arabia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02337881 on ClinicalTrials.gov