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Sacubitril/Valsartan in Resistant Hypertension

NCT04637152 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2025-02-24

No results posted yet for this study

Summary

The present study aims to evaluate the antihypertensive effect of sacubitril/valsartan in patients with resistant hypertension compared to the use of recommended and optimized antihypertensive therapy, through a randomized clinical trial, over 12 weeks.

Conditions

  • Resistant Hypertension
  • Blood Pressure

Interventions

DRUG

Sacubitril-Valsartan

Use of sacubitril/valsartan after suspension of ACE inhibitors or ARBs.

Sponsors & Collaborators

  • Hospital Universitário Professor Edgard Santos

    collaborator OTHER

  • Hospital Geral Roberto Santos

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-11
Primary Completion
2022-07-22
Completion
2022-08-17

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04637152 on ClinicalTrials.gov