Differential Vascular and Endocrine Effects of Valsartan/Sacubitril in Heart Failure With Reduced Ejection Fraction
NCT03168568 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 79
Last updated 2020-11-04
Summary
The objective of this study is to evaluate whether valsartan/sacubitril leads to a superior improvement in endothelial function and endocrine status compared to valsartan alone.
Conditions
Interventions
- DRUG
-
Valsartan/Sacubitril or placebo
tablet (double dummy)
- DRUG
-
Valsartan or placebo
tablet (double dummy)
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of Zurich
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-05-04
- Primary Completion
- 2020-09-05
- Completion
- 2020-09-05
Countries
- Switzerland
Study Locations
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