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Plasma Endostatin Predicts Outcome of Septic AKI

NCT04633746 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2020-11-18

No results posted yet for this study

Summary

Introduction: Acute kidney injury (AKI) occurs up to 50% of patients admitted to intensive care unit. Plasma Endostatin, released from basement membrane of Bowman's capsule, rises early during AKI.

Aim of Work: To investigate the role of the plasma endostatin in the outcome prediction (renal recovery, ICU stay, mortality) of acute kidney injury in patients with sepsis.

Methods: a prospective, observational single center study on 40 patients with Sepsis at the Critical Care Department, Cairo University hospitals between March 2019 and November 2019. Serum plasma endostatin was measured at the day of admission \& every 48hrs (3 samples). APACHE II, SOFA scores were calculated. Forced diuresis was used if indicated.

Conditions

  • Acute Kidney Injury Due to Sepsis

Interventions

DIAGNOSTIC_TEST

measuring plasma Endostatin level

measuring plasma Endostatin level at the time of admission then after 48hrs and 96 hours

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • farouk faris · Cairo University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-20
Primary Completion
2020-06-30
Completion
2020-08-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04633746 on ClinicalTrials.gov