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Characterization of the Liver Parenchyma Using Parametric T1 and T2 Magnetic Resonance Relaxometry

NCT04623528 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 224

Last updated 2020-11-10

No results posted yet for this study

Summary

* To determine normal T1 and T2 values of the liver, and to assess the impact of age and gender
* To determine the relation between markers of right heart decompensation and T1/T2 values of the liver in patients with pulmonary hypertension, patients with dilated cardiomyopathy, and patients with constrictive pericarditis (or constrictive physiology)
* To determine inter/intra-observer reproducibility for liver T1/T2 assessment
* To test/develop multi-feature texture analysis for T1/T2 analysis of the liver and implement machine learning to derive indicative features (MR-derived measures only vs combined with other clinical readouts)

Conditions

  • Cardiomyopathy, Congestive
  • Pulmonary Hypertension
  • Constrictive Pericarditis
  • Cardiomyopathy, Dilated

Interventions

DIAGNOSTIC_TEST

T1 and T2 relaxometry of the liver parenchyma

Evaluate T1 and T2 relaxomatry of the liver parenchyma to depict liver congestion in the different patient groups

Sponsors & Collaborators

Principal Investigators

  • Jan Bogaert, MD · Universitaire Ziekenhuizen KU Leuven

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2020-01-31
Completion
2020-10-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04623528 on ClinicalTrials.gov