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A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome

NCT04618887 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-11-06

No results posted yet for this study

Summary

In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral globus palliotomy) and deep brain stimulation (unilateral globus pallidus) ,in order to get the conclusion of the comparison of the clinical efficacy of the two surgical plans. In addition, possible predictive factors such as age, gender, age of onset, length of disease course, scale baseline score, preoperative brain PET-CT function analysis and other possible predictive factors are added for analysis, in order to find predictive factors that can guide the choice of surgical options.

Conditions

  • Meige Syndrome
  • Meigs Syndrome
  • Meige Disease
  • Meig Syndrome
  • Blepharospasm
  • Blepharospasm of Left Eyelid
  • Blepharospasm of Right Eyelid
  • Blepharospasm of Both Eyelids
  • Blepharospasm Oromandibular Dystonia

Interventions

PROCEDURE

pallidotomy

deep brain nuclei lesion of GPi

PROCEDURE

deep brain stimulation

deep brain stimulation of GPi

Sponsors & Collaborators

  • Peking University People's Hospital

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2022-11-30
Completion
2023-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04618887 on ClinicalTrials.gov