Efficacy of Botulinum Toxin for the Treatment of Dystonia Associated With Parkinson's Disease and Atypical Parkinsonism
NCT04948684 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 63
Last updated 2021-07-02
Summary
Dystonia is a disabling symptom affecting both patients with idiopathic Parkinson's disease (PD) and atypical parkinsonism (AP).
Botulinum toxinum (BoNT), by blocking muscle contraction, is a possible treatment for focal dystonia.
The benefit of BoNT treatment has been proven in some focal dystonia associated with PD or AP.
The investigators aim to give an overview of the efficacy of BoNT in a variety of focal dystonia in a large cohort of parkinsonian patients.
Conditions
- Parkinson Disease
- Atypical Parkinsonism
- Dystonia
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
collaborator OTHER -
Hospital Avicenne
lead OTHER
Principal Investigators
-
Bertrand Degos, MD,PhD · Hospital Avicenne
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-09-01
- Primary Completion
- 2021-02-11
- Completion
- 2021-02-11
Countries
- France
Study Locations
More Related Trials
-
A Study to Assess Treatment Outcomes of abobotulinumtoxinA and onabotulinumtoxinA Treatments in Real Life Practice in Toxin-naïve Adult Patients With Limb Spasticity.
NCT04396704 ·Status: COMPLETED
-
Strategy to Adapt Botulinum Toxin Doses in Dystonia
NCT06386848 ·Status: NOT_YET_RECRUITING
-
Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia
NCT00564681 ·Status: COMPLETED ·Phase: PHASE2
-
Outcome of Botulinum Toxin Treatment for Oromandibular Dystonia
NCT03363113 ·Status: COMPLETED
-
Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain
NCT00178945 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Targeting Methods of Botulinum Toxin Injections for Cervical Dystonia
NCT03946046 ·Status: COMPLETED ·Phase: NA
-
Botulinum A Toxin in Patients With Parkinson's Disease
NCT00822913 ·Status: UNKNOWN ·Phase: PHASE4
-
Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia
NCT03938363 ·Status: COMPLETED ·Phase: NA
-
CLINICAL EFFECT OF BOTULINUM TOXIN TYPE A IN TREATMENT OF SPASTICITY
NCT04673240 ·Status: UNKNOWN
-
Effects of Botulinum Toxin on Muscle and Brain Activity
NCT02837185 ·Status: TERMINATED ·Phase: NA
-
Early Treatment of Post-stroke Spasticity With Botulinum Toxin
NCT04404868 ·Status: COMPLETED
-
Effect of Botulinum Toxin on Muscles of Children With Cerebral Palsy
NCT02853240 ·Status: COMPLETED ·Phase: NA
-
Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease
NCT04277247 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
NCT03992404 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study to Assess the Effectiveness of AboBoNT-A Injections for Adult Lower Limb Spasticity in a Real Life Cohort
NCT04050527 ·Status: COMPLETED
-
Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia
NCT04171258 ·Status: COMPLETED ·Phase: PHASE1
-
OnabotulinumtoxinA in the Management of Psychogenic Dystonia
NCT02618889 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia
NCT00432341 ·Status: TERMINATED ·Phase: PHASE4
-
Botulinum Toxin A to Treat Arm Tremor
NCT02207946 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm
NCT04766723 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of Botox on Reducing Rest Tremor in Parkinson's Disease
NCT03301272 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity.
NCT04936542 ·Status: COMPLETED ·Phase: PHASE4
-
A Multimodal Approach to Cervical Dystonia Treatment With Association of Botulinum Toxin and Motor Learning Techniques
NCT03247868 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke
NCT01392300 ·Status: COMPLETED ·Phase: PHASE3
-
Early Use of Botulinum Toxin in Spasticity Post Stroke.
NCT01882556 ·Status: COMPLETED ·Phase: PHASE2