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Defining Causes of Deaths in South and Southeast Asia

NCT04595656 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3413

Last updated 2026-02-18

No results posted yet for this study

Summary

Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends. Mortality statistics in the populations of Bangladesh, Myanmar and Lao PDR are considered as generally limited and a recent assessment of vital registration systems of those countries reported a poor performance of the death registration system. Majority of deaths occur at home in rural area of those countries without cause of death assigned. To address this problem, the investigators will use verbal autopsy (VA) method developed by WHO to ascertain the cause of a death based on an interview with a family member or caregiver of deceased person to obtain information about causes of death in study rural communities. Death related to a specific cause will be defined by ICD-10 codes and described as primary, secondary or underlying COD. The study is planned to conduct in approximately 390 rural village communities covered by Southeast Asia clinical trial network (SEACTN) network in proposed 3 countries. The study findings will help establish a better understanding in signs, symptoms, medical history and circumstances preceding death; prioritize future interventions for early and effective diagnostics and treatment for diseases and how to keep mortality surveillance ongoing in study rural settings.

This study is funded by Welcome Trust. Welcome Trust grant reference number is \[215604/Z/19/Z\].

Conditions

  • Cause of Mortality
  • Cause of Neonatal Death
  • Cause of Child Death
  • Cause of Maternal Death
  • Cause of Adult Death

Interventions

OTHER

verbal autopsy interview

The study involves filling of verbal autopsies for deaths in SEACTN villages. This is an observational study being conducted as a substudy of rural febrile project of SEACTN program.

Sponsors & Collaborators

  • University of Oxford

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2024-04-30
Completion
2024-04-30

Countries

  • Bangladesh
  • Burma
  • Cambodia
  • Laos
  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04595656 on ClinicalTrials.gov