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Excessive Supraventricular Activity and Atrial Fibrillation

NCT04593498 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2024-03-06

No results posted yet for this study

Summary

The aim of the proposed study is to determine if individuals with excessive supraventricular ectopic activity (ESVEA) on Holter recording should be subjected to prolonged screening with Event loop recorder in order to detect previously undiagnosed Atrial fibrillation / flutter. Other biomarkers such as plasma biomarkers, high-end echocardiography and assessment of blood pressure and atrial stiffness will be studied and compared in ESVEA and control group as well as progression of atrial cardiomyopathy in ESVEA patients.

Conditions

  • Atrial Fibrillation
  • Atrial Flutter
  • Supraventricular Beat, Premature
  • Premature Supraventricular Beats
  • Premature Atrial Complex
  • Extrasystole, Atrial

Interventions

DIAGNOSTIC_TEST

Holter recording

Holter recording with Zenicor Flex ECG during 14 days.

DIAGNOSTIC_TEST

Echocardiography (Echo)

Echocardiography: Comprehensive transthoracic echocardiography with special focus on atrial dimension and function.

DIAGNOSTIC_TEST

Blood sample

Blood sample: 2 x 10 ml EDTA plasma sampled from venous blood at index and at 21 months. Troponin T, NTproBNP, Na, K, Creatinine. Sample for Biobank for future analysis.

DIAGNOSTIC_TEST

24 hour ambulatory blood pressure monitoring And Arteriograph

To assess artery stiffness.

Sponsors & Collaborators

Eligibility

Min Age
70 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-11-01
Primary Completion
2026-12-31
Completion
2028-02-15

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04593498 on ClinicalTrials.gov