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Obesity and Pediatric Multiple Sclerosis

NCT04593082 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 116

Last updated 2026-04-29

No results posted yet for this study

Summary

Obesity is one possible contributor to severity of multiple sclerosis and progression of the disease. We already know that obesity is a risk determinant for acquiring MS, yet the impact of obesity on pediatric MS disease expression and course is unknown. This study will evaluate the relationship between obesity, obesity-derived inflammatory mediators, and imaging metrics of MS severity in children. Understanding how childhood obesity contributes to MS severity/progression may yield fundamental insights into disease pathobiology - which may thereby lead to effective strategies for halting its progression in its earliest stages.

Conditions

Sponsors & Collaborators

Principal Investigators

  • J Nicholas Brenton, MD · University of Virginia

Eligibility

Min Age
10 Years
Max Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-06-03
Primary Completion
2026-05-21
Completion
2027-06-01

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04593082 on ClinicalTrials.gov