Hallucinations in Parkinson's Disease

Summary

Investigation on how robotically mediated sensorimotor stimulation induces and triggers presence hallucinations in different clinical groups of parkinsonian patients, and in aged-matched controls

Conditions

• Parkinson Disease Psychosis

Interventions

BEHAVIORAL

Clinical and neuropsychological assessments

The assessment of disease state, clinical condition, and of cognitive and neuropsychological attributes.

BEHAVIORAL

Induction of PH and associated bodily states

Assessment of subjective sensitivity to the induction of the PH and associated bodily states, for different populations of PD patients and healthy aged-matched controls

OTHER

Resting-state fMRI acquisition

Investigation of neural mechanisms at rest, that are potentially disrupted at different degrees, for the different clinical groups of PD patients, compared to the healthy aged-matched controls

OTHER

Induction of PH and associated bodily states (MRI)

Assessment of subjective sensitivity to the induction of the PH and associated bodily states, for different populations of PD patients and healthy aged-matched controls Assessment and comparison of the neural mechanisms responsible for the induction of the PH and associated bodily illusions, in different groups of PD patients and healthy aged-matched controls

Sponsors & Collaborators

• University Hospital, Geneva

  collaborator OTHER

• Hôpital du Valais

  collaborator OTHER

• Insel Gruppe AG, University Hospital Bern

  collaborator OTHER

• Centre Hospitalier Universitaire Vaudois

  collaborator OTHER

• Hospital de Sant Pau

  collaborator OTHER

• Olaf Blanke

  lead OTHER

Principal Investigators

• Olaf Blanke · Ecole Polytechnique Fédérale de Lausanne

Study Design

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-08-17

Primary Completion

2021-12-01

Completion

2021-12-01

Countries

• Spain
• Switzerland

Study Locations