Furosemide as Supportive Therapy for COVID-19 Respiratory Failure
NCT04588792 · Status: TERMINATED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2023-12-11
Summary
This double-blind, placebo-controlled, randomized, parallel-group phase 2/3 study will study the utility of nebulized furosemide for pulmonary inflammation in Intubated, mechanically ventilated Patients with COVID-19.
Conditions
- Covid19
- Respiratory Failure
Interventions
- DRUG
-
Nebulized Furosemide
Furosemide administered by nebulization through the ventilator circuit
- DRUG
-
Nebulized Saline
Saline administered by nebulization through the ventilator circuit
Sponsors & Collaborators
-
University Health Network, Toronto
collaborator OTHER -
Dr. John Muscedere
lead OTHER
Principal Investigators
-
John Muscedere, MD · Queens University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-04-16
- Primary Completion
- 2023-02-01
- Completion
- 2023-04-30
Countries
- Canada
Study Locations
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