Improved Bowel Preparation Method for Colonoscopy Based on Different Risk Stratification

Summary

The purpose of this study is to evaluate the efficacy of polyethylene glycol（PEG） combined with lactulose for bowel preparation before colonoscopy in low-risk patients and high-risk patients.

Conditions

• Bowel Preparation Before Colonoscopy

Interventions

DRUG

PEG

Patients began to drink 1 L of PEG at 8:00 PM on the day before colonoscopy at a rate of 250 mL every 10- 15 minutes. On the day of the procedure, patients took the remaining 2 L of PEG 4-6 hours before colonoscopy.

DRUG

PEG+lactulose

On the day before colonoscopy , Patients took 45 mL lactulose solution at 7:00 PM. And then Patients began to drink 1 L of PEG at 8:00 PM at a rate of 250 mL every 10- 15 minutes. On the day of the procedure, patients took 45 mL lactulose solution and the remaining 2 L of PEG 4-6 hours before colonoscopy.

Sponsors & Collaborators

• Hubei Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Wuhan Central Hospital

  collaborator OTHER

• Wuhan Third Hospital

  collaborator OTHER

• The General Hospital of Central Theater Command

  collaborator OTHER

• The Third People's Hospital of Hubei Province

  collaborator OTHER

• Wuhan Puren Hospital

  collaborator OTHER

• Wuhan Puai Hospital

  collaborator UNKNOWN

• Tian You Hospital Affiliated to Wuhan University of Science and Technology

  collaborator UNKNOWN

• Wuhan Red Cross Hospital

  collaborator UNKNOWN

• Renmin Hospital of Wuhan University

  lead OTHER

Principal Investigators

• Mingkai Chen, M.D · Renmin Hospital of Wuhan University

Study Design

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-08-06

Primary Completion

2021-08-15

Completion

2021-08-15

Countries

• China

Study Locations