Bevacizumab Plus EGFR-TKIs in Chinese Patients With EGFR-mutant NSCLC: a Real-world Study
NCT04575415 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 272
Last updated 2020-10-20
Summary
This study is a prospective, multicenter, real-world study to investigate the efficacy and safety of bevacizumab plus epidermal growth factor (EGFR) Tyrosine Kinase Inhibitors in Chinese Patients With Stage IIIB/IV EGFR-mutant Non-small Cell Lung Cancer.
Conditions
Interventions
- DRUG
-
Bevacizumab 15mg/kg or clinical routine dose by intravenous drip infusion on day 1 of a 21-day cycle
- DRUG
-
Erlotinib
Erlotinib 150mg, orally once a day
- DRUG
-
Gefitinib
Gefitinib 250mg, orally once a day
- DRUG
-
Icotinib
Icotinib 125mg three times a day
- DRUG
-
Afatinib
Afatinib 40 mg or clinical routine dose once daily
- DRUG
-
Dacomitinib
Dacomitinib 45mg or clinical routine dose once daily
- DRUG
-
Osimertinib 80 mg once daily
Sponsors & Collaborators
-
Guangdong Association of Clinical Trials
lead OTHER
Principal Investigators
-
Qing Zhou, PhD · Guangdong Provincial People's Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-10-07
- Primary Completion
- 2023-05-31
- Completion
- 2023-12-31
- FDA Drug
- Yes
Countries
- China
Study Locations
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