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Multimodal Neurobiological Approaches to Explore the Gene-Environment Interactions in ADHD

NCT04571125 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 202

Last updated 2024-03-19

No results posted yet for this study

Summary

Previous studies have demonstrated significant associations of attention-deficit hyperactivity disorder (ADHD) with monoamine transporter genes, including dopamine transporter gene (DAT1), norepinephrine transporter gene (SLC6A2), and serotonin transporter gene (SLC6A4) as well as the important role of environmental factors in the pathogenesis of ADHD. Hence, investigating how genes and environments interact with each other may contribute to the understanding of the pathophysiological mechanisms of ADHD. In this 3-year project, investigators will explore the complex gene-environment interplay in ADHD with multimodal neurobiological approaches, including neuropsychology, neuroimaging, and metabolites, in order to identify the crucial pathophysiological pathways from genes to the brain.

Conditions

  • Monoamine Transporter Genes
  • Environmental Factors

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Susan Shur-Fen Gau, MD, PhD · Department of Psychiatry, National Taiwan University Hospital

Eligibility

Min Age
7 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-09-19
Primary Completion
2023-07-05
Completion
2023-07-05

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04571125 on ClinicalTrials.gov