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PIC and Its Role in Progression of Pathological Myopia

NCT04561869 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 39

Last updated 2021-06-18

No results posted yet for this study

Summary

Aim of the work PIC in pathological myopia has not been well documented due to difficult in diagnosis we conducted this retrospective study to characterize the clinical features of PIC in high myopic eye.

* To show the diagnostic criteria of PIC lesions in high myopic patients.
* Find out the prevalence of PIC related 'patchy atrophy'
* To determine risk factor for developed PIC in a series of highly myopic patients.
* Role of PIC in progression of high myopia.
* Calculate the progression rate of PIC related lesion, by the size change during follow-up.
* Search about complication of PIC in myopia. Patient and Methods This retrospective observational case series study included patients with high myopia who had been examined and followed-up in the High Myopia Clinic of the Tokyo Medical and Dental University. Approval from Ethics Committee of Tokyo Medical and Dental University was obtained, adhering to the tenets of Declaration of Helsinki. Signed informed consent documentation was obtained from all participants.

All study participants underwent a detailed ophthalmologic examination at baseline and at each follow-up visit. The examinations included measurements of best-corrected visual acuity (BCVA) using a Landolt C chart, refraction, slit lamp biomicroscopy, biometry for determination of axial length, (IOL Master; Carl Zeiss Meditec Co, Jena, Germany), fundus examination in medical mydriasis, fluorescein angiography, was performed with and colour fundus photography , and assessment of fundus autofluorescence (TRC-50DX; Topcon, Tokyo, Japan) a or the Heidelberg Spectralis HRA system. Swept source Optical coherence tomography (OCT) used in assessment of the RPE and photoreceptors using a (DRI-OCT;Topcon, Tokyo, Japan). As scanning protocols, 9 mm or 6 mm radial with 12 equal meridian scans were performed. The swept-source OCT device has an A-scan repetition rate of 100 000 Hz, and its light source operates in the wavelength range of 1 μm.

Conditions

  • Punctate Inner Choroidopathy

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Shymaa Kl Hady, As Lec · Department of Ophthalmology , Assiut University

  • Kyoko Oh Matsui, Prof · ,Department of Ophthalmology Tokyo Medical and Dental University

  • Omar Mo Ali, Prof · Department of Ophthalmology , Assiut University

  • Ehab Is Wasfi, As prof · Department of Ophthalmology , Assiut University

  • Mahmoud Fa Rateb, As prof · Department of Ophthalmology , Assiut University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-15
Primary Completion
2021-10-15
Completion
2021-11-15

Countries

  • Japan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04561869 on ClinicalTrials.gov