A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer
NCT04528225 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 729
Last updated 2026-01-13
Summary
This study is to prospectively investigate the incidence of hypothyroidism after postoperative radiotherapy and identify risk factors for development of hypothyroidism. Patients with breast cancer treated with surgery followed by radiotherapy is enrolled. Thyroid function was assessed at baseline and different times after radiotherapy. The radiation technique, thyroid dose parameters and hypothyroidism are prospective evaluated, and the dose-effect relationship is analyzed.
Conditions
- Breast Neoplasms
- Hypothyroidism
- Radiation Toxicity
Sponsors & Collaborators
-
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
lead OTHER
Principal Investigators
-
Shu-lian Wang, M.D. · Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-15
- Primary Completion
- 2020-02-24
- Completion
- 2020-02-24
Countries
- China
Study Locations
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