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Metals/Vitamins Levels in NTD

NCT04523233 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2021-08-31

No results posted yet for this study

Summary

Introduction: Heavy metals important pollutants produced from anthropogenic activities, has been suggested to be embryotoxic and fetotoxic in a lot of studies. The aims of this study were to determine the levels of trace elements and heavy metals, namely folic acid, zinc (Zn), molybdenum (Mo), vanadium (V), strontium (Sr), aluminium (Al), tin (Sn), antimony (Sb), mercury (Hg), calcium (Ca), iron ( Fe), magnesium (Mg), phosphorus (P), barium (B) and selenium (Se), in the amniotic fluid of pregnant women, and to investigate their relationship with neural tube defects (NTDs).

Methods: The study will be included 70 pregnant women whose fetuses were complicated with NTDs (study group) and 70 pregnant women with unaffected healthy fetuses (control group). The samples levels of elements and vitamins will be measured using inductively coupled plasma-mass spectrometry and will be compared between the two groups.

Conditions

  • Neural Tube Defects

Interventions

DIAGNOSTIC_TEST

Amniocentesis

Amniocentesis is a procedure in which amniotic fluid is removed from the uterus for testing or treatment.

Sponsors & Collaborators

  • The Scientific Research Project Fund of Yozgat Bozok University

    collaborator UNKNOWN

  • Cengiz Gokcek Women's and Children's Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-25
Primary Completion
2021-10-30
Completion
2022-02-28

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04523233 on ClinicalTrials.gov