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CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery

NCT04503720 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2024-07-12

No results posted yet for this study

Summary

Major abdominal surgery is associated with significant complications which may lead to morbidity and mortality. Pain experienced after surgery affects the recovery from surgery.

Our study aims to evaluate the current gold standard of PCA morphine infusion against a continuous wound infusion (CLoWI). The use of CLoWI negates the side-effects of opioids, and will be the first randomised controlled trial to compare PCA (Morphine) with CLoWI-LA (Ropivacaine).

Conditions

  • Surgical Wound
  • Post-Op Complication
  • Opioid Use

Interventions

DEVICE

CLoWI

Patients will receive a continuous wound infusion with ropivacaine and normal saline in the PCA pump.

DEVICE

PCA

Patients will receive a continuous wound infusion with normal saline and morphine in the PCA pump.

Sponsors & Collaborators

  • JurongHealth

    lead OTHER_GOV

Principal Investigators

  • Christopher Keh, FRCS · Ng Teng Fong General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
SINGLE_GROUP

Eligibility

Min Age
21 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-12-01
Primary Completion
2022-06-30
Completion
2022-06-30

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04503720 on ClinicalTrials.gov