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Short Term Induction of Ketosis in PKD

NCT04472624 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2021-09-14

No results posted yet for this study

Summary

Recently, it has been shown that ketose-inducing dietary interventions slow disease progression in animal models of polycystic kidney disease (PKD), even when the state of ketosis is only induced for a short period of time. The present study aims to investigate the effects of short term ketosis on total kidney volume (TKV) (and other parameters) in 10 ADPKD-patients with rapidly progressive disease.

Conditions

  • ADPKD

Interventions

OTHER

Fasting

Acute fasting for 72 hours

OTHER

Ketogenic diet

Intake of a ketogenic diet for 14 days

Sponsors & Collaborators

  • University of Cologne

    lead OTHER

Principal Investigators

  • Roman-Ulrich Müller, Prof. · Department II of Internal Medicine, University of Cologne

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2021-07-01
Completion
2021-07-01

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04472624 on ClinicalTrials.gov