Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR
NCT04461223 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 55
Last updated 2020-07-08
Summary
using a contrast-enhanced (CE) cardiac magnetic resonance imaging(CMR) which included the measurement of T1 mapping, T2 mapping, T2\* mapping and late gadolinium enhancement(LGE) sequences, as well as LVEF and extracellular volume(ECV) to evaluate the respective changes before and after anthracycline chemotherapy.
Conditions
- Cardiotoxicity
- Osteosarcoma
- Myocardial Injury
- Chemotherapy Induced Systolic Dysfunction
- Doxorubicin Induced Cardiomyopathy
Interventions
- DIAGNOSTIC_TEST
-
contrast-enhanced cardiac magnetic resonance imaging(MAGNETOM Aera 1.5T)
CMR T1 mapping, T2mapping, T2\* mapping, LGE, ECV
Sponsors & Collaborators
-
Second Affiliated Hospital, School of Medicine, Zhejiang University
lead OTHER
Eligibility
- Min Age
- 8 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-12-01
- Primary Completion
- 2021-12-01
- Completion
- 2021-12-01
Countries
- China
Study Locations
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