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The Correlations of FeNO, Blood Eosinophils and Lung Function in Well-controlled Asthma

NCT04454385 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 84

Last updated 2021-01-15

No results posted yet for this study

Summary

In Asthma, the levels of exhaled FeNO is correlated to sputum eosinophils particularly in the patient with poor controlled asthma or severe asthma. Moreover, the blood eosinophils had been studied that are also correlated to sputum eosinophils in similar patients group. According to well controlled asthma, althoug hin clinical practice guidelines recommend that the stepping down therapy should be considered to those patients due to the risks or costs of daily treatment, there is previous study has been shown that the airway hyperresponsiveness and sputum eosinophilia are predictors of loss of control during dose reduction. And, these tests are not readily available in primary care. However, there is limit number of clinical study to study the correlation of biologic markers among the patients with well controlled level before the stepping down management.

Conditions

Interventions

DIAGNOSTIC_TEST

Patients with well controlled asthma

Patients with well controlled asthma The following parameters are to be evaluated: Blood eosinophils FeNO Findings on lung function test

Sponsors & Collaborators

  • Hat Yai Medical Education Center

    lead OTHER

Eligibility

Min Age
15 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-01
Primary Completion
2020-10-31
Completion
2020-10-31

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04454385 on ClinicalTrials.gov