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Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome

NCT04452266 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2021-03-09

No results posted yet for this study

Summary

Lynch Syndrome increases Endometrial Cancer Occurrence in women due to failure in MisMatch Repair System. Lifetime Cumulative risk of developing endometrial Cancer is approximatively 40% in women with Lynch Syndrome.

Endometrial cancer is the third women cancer in France. Many risk factors are known in general population. Lots of factors are related to over exposure to estrogen.

Data about influence of general risk factors in Women with Lynch Syndrome are poor. Recently, a cohort study appears to have shown a significant decrease in the risk of endometrial cancer with multiparity, the use of hormonal contraception and late menopause in Lynch women. The impact of weight and certain metabolic parameters on the occurrence of endometrial cancers remains poorly known to this day.

Conditions

Interventions

OTHER

questionnaire assesment

Each patient will to answer questions about their medical history.

Sponsors & Collaborators

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Solveig MENU-HESPEL, MD · University Hospital, Lille

Eligibility

Min Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-08-14
Primary Completion
2020-10-20
Completion
2020-10-20

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04452266 on ClinicalTrials.gov