Precision Medicine Study on Cardiovascular Disease (PRECISE)
NCT04434911 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 20000
Last updated 2021-03-09
Summary
Cardiovascular diseases are the leading cause of death in China and have become a financial burden on society under the traditional medical model. A new and sustainable medical model is needed to solve this dilemma, for which precision medicine models have great potential. Monogenic cardiovascular disease is the first field to be broken through in precision medicine at this stage, and it is also the field where precision medicine is most likely to be successfully transformed into clinical application, including genetic diagnosis, molecular typing, risk stratification, genetic interruption and individualized treatment.
Conditions
Sponsors & Collaborators
-
China National Center for Cardiovascular Diseases
lead OTHER_GOV
Principal Investigators
-
Lei Song, MD. ph.D · Chinese Academy of Medical Sciences, Fuwai Hospital
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-03-10
- Primary Completion
- 2025-10-10
- Completion
- 2030-10-10
Countries
- China
Study Locations
More Related Trials
-
Early rhBNP on Myocardial Work in Patients With STEMI
NCT04157868 ·Status: UNKNOWN ·Phase: PHASE4
-
Real-world Study on Edoxaban Treatment for Patients With Non-valvular Atrial Fibrillation in China
NCT04747496 ·Status: COMPLETED
-
Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.
NCT03388593 ·Status: RECRUITING ·Phase: PHASE3
-
An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM
NCT06116968 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure
NCT04468529 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40%
NCT04986202 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effective Study of ARNI on Ventricular Arrhythmia in HFrEF Patients With ICD or CRT-D (RHYTHM)
NCT04491136 ·Status: TERMINATED ·Phase: PHASE4
-
Effect of Recombinant Human Brain Natriuretic Peptide on Ventricular Remodeling and Cardiac Function in Patients With Acute Anterior Myocardial Infraction Undergoing Percutaneous Coronary Intervention
NCT06463808 ·Status: RECRUITING
-
Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
NCT01131637 ·Status: TERMINATED ·Phase: PHASE3
-
Clinical and Metabonomics Study on the Treatment of Heart Failure After Myocardial Infarction With Modified Wenxin Decoction
NCT04667598 ·Status: UNKNOWN ·Phase: PHASE2
-
Registry Study of Pharmacotherapy and Clinical Outcomes in Elderly Patients With Coronary Heart Disease (PHARM-ageing)
NCT05246722 ·Status: NOT_YET_RECRUITING
-
Effect of Dapagliflozin on VT in Patients With Heart Failure.
NCT05550441 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Sodium Glucose Cotransporter 2 Inhibitiors on Left Ventricular Remodeling Among Diabetic and Non Diabetic Patients With Chronic Heart Failure
NCT06137430 ·Status: NOT_YET_RECRUITING
-
Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure
NCT05111769 ·Status: UNKNOWN ·Phase: NA
-
Forxiga HF General Drug Use-Results Study
NCT04865406 ·Status: COMPLETED
-
Program of Angiotensin-Neprilysin Inhibition in Admitted Patients With Worsening Heart Failure (PREMIER)
NCT05164653 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
The Clinical Study of the Efficacy and Safety of L-Carnitine Injection in Treatment of Heart Failure
NCT01580553 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure
NCT00813202 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of dapaglifloziN Therapy on Myocardial Perfusion Reserve in Prediabetic Patients With Stable coronarY Artery Disease
NCT04330079 ·Status: TERMINATED ·Phase: PHASE4
-
The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes
NCT04549415 ·Status: COMPLETED ·Phase: PHASE4
-
The Comparative Effectiveness Between ARNI and ACE Inhibitor/ARB Medication in Patient With HFrEF
NCT05329727 ·Status: RECRUITING
-
A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT
NCT04766892 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Mechanism of Exenatide on Improving Heart Function in Type 2 Diabetes With Heart Failure Patients
NCT02344641 ·Status: UNKNOWN ·Phase: NA
-
Study of Qiliqiangxin Capsule to Treat Dilated Cardiomyopathy
NCT01293903 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
NCT05949801 ·Status: COMPLETED ·Phase: PHASE3