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The Assessment of the Diagnosis and Prognosis of Patients With Alzheimer Disease or Parkinson Disease With Cognitive Impairment by Using Diffusion MRI

NCT04434898 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 212

Last updated 2021-08-06

No results posted yet for this study

Summary

The hypothesis is that the differential extent of microstructural damages in the affected brain regions can be specific to the disease of interest and could reflect the clinical severity. Therefore, the investigator propose that whole brain parcellation of diffusion MRI can be used to improve diagnosis and prediction of clinical outcomes in Parkinson's Disease.

1. A regression model between clinical severity and two year clinical outcomes and diffusion properties from multiple parcellated regions will be developed.
2. Blind validation will be performed.

Conditions

  • Alzheimer Disease
  • Parkinson Disease

Sponsors & Collaborators

  • Chang Gung Memorial Hospital

    lead OTHER

Eligibility

Min Age
50 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2018-10-01
Completion
2020-09-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04434898 on ClinicalTrials.gov