Respiratory Complications in ALS
NCT04430686 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2021-09-22
Summary
Respiratory failure is the leading cause of death in motor neuron disease (MND) patients. Symptoms of respiratory dysfunction in MND patients include sleep disturbance, excessive daytime somnolence, morning headaches and cognitive changes. Almost all MND patients will develop respiratory problems during the course of their disease. In a small percentage of MND patients, respiratory failure may present as the primary symptom at onset, whereas more commonly it develops later in the disease.
Conditions
- Motor Neuron Disease
- Pneumonia
Interventions
- OTHER
-
Questionaires
Any validated functional rating scale, such as the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) or the ALSFRS-Revised (if available)
Sponsors & Collaborators
-
Liverpool University Hospitals NHS Foundation Trust
lead OTHER_GOV
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-01
- Primary Completion
- 2021-09-01
- Completion
- 2021-09-01
Countries
- United Kingdom
Study Locations
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