Chloroquine + Losartan Compared to Chloroquine Alone for the Treatment of COVID-19 Pneumonia
NCT04428268 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2021-02-18
Summary
Study design Phase 2, double blinded, single-center, 1:1 randomized clinical trial of Chloroquine vs Chloroquine/losartan for the treatment of SARS-CoV-2 pneumonia in non-critically ill subjects
Conditions
Interventions
- DRUG
-
Chloroquine Phosphate Tablets
Orally administered
Sponsors & Collaborators
-
Hospital Universitario Dr. Jose E. Gonzalez
lead OTHER
Principal Investigators
-
Adrian Camacho Ortiz, MD · Hospital Universitario "Dr. Jose Eleuterio Gonzalez", UANL
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-10
- Primary Completion
- 2020-06-10
- Completion
- 2021-02-16
Countries
- Mexico
Study Locations
More Related Trials
-
Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2
NCT04323527 ·Status: COMPLETED ·Phase: PHASE2
-
Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly
NCT01785979 ·Status: WITHDRAWN ·Phase: PHASE3
-
Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 Infection
NCT04341727 ·Status: TERMINATED ·Phase: PHASE3
-
Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia
NCT00084240 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection
NCT04481633 ·Status: COMPLETED ·Phase: NA
-
A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine
NCT00844207 ·Status: COMPLETED ·Phase: PHASE1
-
Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America
NCT00084227 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection
NCT02691910 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Add on to Azythromycine, Phytomedicine and/or Antimalarial Drug vs Hydroxychloroquine in Uncomplicated COVID-19 Patients
NCT04502342 ·Status: UNKNOWN ·Phase: PHASE2
-
Asymptomatic COVID-19 Trial
NCT04374552 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus (COVID-19)
NCT04322123 ·Status: COMPLETED ·Phase: PHASE3
-
Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
NCT03278808 ·Status: WITHDRAWN ·Phase: PHASE2
-
Chloroquine Phosphate Against Infection by the Novel Coronavirus SARS-CoV-2 (COVID-19): The HOPE Open-Label, Non Randomized Clinical Trial
NCT04344951 ·Status: TERMINATED ·Phase: PHASE2
-
Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
NCT04374903 ·Status: WITHDRAWN ·Phase: NA
-
Efficacy of Azithromycin-associated Hydroxychloroquine Therapy Given in General Practice in Early-stage Disease in COVID-19 Patients
NCT04371406 ·Status: WITHDRAWN ·Phase: PHASE3
-
Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India
NCT00074841 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Chloroquine for Malaria in Pregnancy
NCT01443130 ·Status: COMPLETED ·Phase: PHASE3
-
Hidroxicloroquina With Azitromicina Versus Hidroxicloroquina and Placebo Int Patients With Mild COVID-19
NCT04964583 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria
NCT00282919 ·Status: COMPLETED ·Phase: PHASE2
-
PRophylaxis of Exposed COVID-19 Individuals With Mild Symptoms Using choloroquinE Compounds
NCT04351191 ·Status: TERMINATED ·Phase: PHASE4
-
Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19
NCT04362332 ·Status: TERMINATED ·Phase: PHASE4
-
Efficacay of Chloroquine or Hydroxychloroquine in COVID-19 Treatment
NCT04353336 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine
NCT00323375 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Role of Chloroquine for Malaria Elimination
NCT02698748 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy
NCT05443178 ·Status: RECRUITING ·Phase: PHASE1