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Biological Mechanisms in Afebrile P. Falciparum Malaria

NCT04422015 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 475

Last updated 2023-09-01

No results posted yet for this study

Summary

This project aims to disentangle the role of host immune resistance and disease tolerance in afebrile malaria infections, with the goal of guiding context-adapted tactics to target this hidden reservoir, as well as to develop new approaches to clear malaria infection and reduce its severity through host-directed therapies.

Conditions

  • Falciparum Malaria

Interventions

OTHER

No intervention

No intervention

Sponsors & Collaborators

  • Centro de Investigação em Saúde de Manhiça

    collaborator OTHER

  • Stanford University

    collaborator OTHER

  • University of Florida

    collaborator OTHER

  • Alfredo Mayor

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-03-01
Primary Completion
2021-03-31
Completion
2021-03-31

Countries

  • Mozambique

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04422015 on ClinicalTrials.gov