RAS and Coagulopathy in COVID19
NCT04419610 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2024-05-03
Summary
To determine whether the coagulopathy associated with COVID-19 infection is driven by overactivation of the renin angiotensin system (RAS)
Conditions
Interventions
- BIOLOGICAL
-
TRV027
peptide for infusion
- OTHER
-
sodium chloride 0.9%
placebo comparator for infusion
Sponsors & Collaborators
-
Imperial College London
lead OTHER
Principal Investigators
-
DAVID OWEN · National Health Service, United Kingdom
-
Katrina Pollock · National Health Service, United Kingdom
Study Design
- Allocation
- RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-10-09
- Primary Completion
- 2021-05-12
- Completion
- 2021-05-12
- FDA Drug
- Yes
Countries
- United Kingdom
Study Locations
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