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Domiciliary Versus Hospital Management of PPROM

NCT04413019 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3662

Last updated 2021-01-06

No results posted yet for this study

Summary

This study is designed to compare efficacy \& safety of planned domiciliary versus hospital care for women with preterm prelabor rupture of the membranes (PPROM) on fetal, neonatal and maternal outcome.

Conditions

  • Preterm Premature Rupture of Membrane

Interventions

OTHER

Clinical follow up

Patients recruited in this study commenced antibiotic treatment according to the recent guidelines : * Erythromycin 250 mg 4 times daily for 10 days following the diagnosis of PPROM, or until the women is established labor (whichever sooner) * Penicillin may be used in patients who can't tolerate erythromycin * In cases of penicillin allergy: Cefazolin 1 g intravenously every 8 hours for 48 hours, followed by cephalexin 500 mg orally four times daily for five days. These drugs provide coverage for both GBS and Escherichia coli, the two major causes of neonatal infection.

Sponsors & Collaborators

  • Ahmed Mohammed Selim

    lead OTHER

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2020-10-01
Completion
2020-10-20

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04413019 on ClinicalTrials.gov