Anticoagulant Therapy and 28-days Mortality in Critically Ill COVID-19 Patients
NCT04412304 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 166
Last updated 2020-06-22
Summary
The aims of the study are to to associate anticoagulation (AC) regime with outcome in critically ill patients with Covid-19. This will be done by describe baseline characteristics and comorbidities before hospital admission, level of organ support and dose of AC treatment and associate this with 28 days survival, survival outside ICU, thromboembolic event and bleeding complications.
Conditions
Interventions
- DRUG
-
Dose of Tinzaparin or Dalteparin
The patients will be categorised into three groups depending on initial regime of anticoagulants after arrival in the ICU.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Maria Cronhjort, PhD · Karolinska Institutet, Department of Clinical Science and Education
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-06
- Primary Completion
- 2020-04-30
- Completion
- 2020-05-28
Countries
- Sweden
Study Locations
More Related Trials
-
Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial
NCT04409834 ·Status: COMPLETED ·Phase: PHASE4
-
D-dimer to Improve Anticoagulation Outcome During ECMO loNg-term supporteD
NCT03261284 ·Status: UNKNOWN ·Phase: NA
-
Evaluating Dose Regimen of Intravenous Unfractionated Heparin and Low Molecular Weight Heparin in Critical Ill Patients Versus Critical Ill COVID-19 Patients Using Anti-Xa Levels.
NCT05224388 ·Status: COMPLETED
-
Thromboprophylaxis in Critically Ill Patients
NCT00437697 ·Status: TERMINATED ·Phase: PHASE4
-
Intensive Dose Tinzaparin in Hospitalized COVID-19 Patients
NCT05036824 ·Status: UNKNOWN
-
Increased Risk of VTE and Higher Hypercoagulability in Patients Recovered in ICU and in Medical Ward for COVID-19
NCT04359212 ·Status: COMPLETED
-
Monitoring Anticoagulation in Patients on ECMO for Severe Lung Failure
NCT06038682 ·Status: COMPLETED
-
Effect of Tinzaparin on Inflammatory Biomarkers During the Acute Phase of Deep Vein Thrombosis
NCT04741464 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19
NCT04745442 ·Status: COMPLETED ·Phase: PHASE2
-
AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia
NCT05848713 ·Status: RECRUITING ·Phase: PHASE3
-
Impact of an Intensified Thromboprofylaxis Protocol in COVID-19
NCT04394000 ·Status: COMPLETED
-
Safety and Efficacy of Therapeutic Anticoagulation on Clinical Outcomes in Hospitalized Patients With COVID-19
NCT04377997 ·Status: UNKNOWN ·Phase: PHASE2
-
New Anticoagulation Strategies of VV-ECMO
NCT03497338 ·Status: WITHDRAWN
-
Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure
NCT05540834 ·Status: RECRUITING ·Phase: PHASE2
-
Prevalence of Severe Bleeding in COVID-19 Patients Treated With Higher Than Recommended Thromboprophylaxis Doses
NCT04380779 ·Status: COMPLETED
-
A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic
NCT04444700 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19
NCT04416048 ·Status: TERMINATED ·Phase: PHASE2
-
High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy
NCT04408235 ·Status: UNKNOWN ·Phase: PHASE3
-
Thrombosis and Covid-19
NCT04366778 ·Status: COMPLETED
-
Long-Term Low-Molecular-Weight Heparin Versus Oral Anticoagulants in Deep Venous Thrombosis
NCT00689520 ·Status: COMPLETED ·Phase: PHASE4
-
Full Anticoagulation Versus Prophylaxis in COVID-19: COALIZAO ACTION Trial
NCT04394377 ·Status: COMPLETED ·Phase: PHASE4
-
COVID-19 and Venous Thromboembolism Risk
NCT04569344 ·Status: COMPLETED
-
Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation
NCT04133844 ·Status: COMPLETED
-
COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications
NCT04535128 ·Status: COMPLETED
-
Coagulopathy of COVID-19: A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care
NCT04362085 ·Status: COMPLETED ·Phase: PHASE3