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Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

NCT04401345 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 258

Last updated 2021-02-21

No results posted yet for this study

Summary

This is prospective randomised double blind study conducted in parturients planned for non-elective caesarean section under spinal anaesthesia. Glycopyrrolate group will receive 0.2 mg of Glycopyrrolate before start of phenylephrine infusion. Control group will receive 0.2 ml of Normal Saline before start of phenylephrine infusion. Total amount of vasopressors required i.e. ephedrine or phenylephrine will recorded in the form of phenylephrine equivalent during intraoperative period.

Conditions

  • Glycopyrrolate
  • Post-spinal Hypotension
  • Effect of Drug
  • Hemodynamic Instability

Interventions

DRUG

Glycopyrrolate 0.2 MG/ML

In this group, the patients will receive glycopyrrolate 0.2 mg in 1 ml

DRUG

Normal saline

In this group, the patients will receive 1 ml of 0.9% normal saline

Sponsors & Collaborators

  • Rajesh Deshar

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-01
Primary Completion
2021-01-31
Completion
2021-01-31

Countries

  • Nepal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04401345 on ClinicalTrials.gov