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Using Cotyledon Perfusion to Study Drugs Transfer Across the Placenta

NCT04400084 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2025-09-12

No results posted yet for this study

Summary

Drug prescriptions are usual during pregnancy however women and their fetuses still remain an orphan population with regard to drugs efficacy and safety clinical studies. Most xenobiotics diffuse through the placenta and some of them can alter fetus development resulting in structural abnormalities, growth or functional deficiencies. The aim of the study is to study the drug transfer using human placenta after delivery.

Conditions

  • Normal Pregnancy

Interventions

OTHER

Placenta perfusion

Placenta perfusion in double closed circuit, during 3 hours

Sponsors & Collaborators

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-05
Primary Completion
2030-06-30
Completion
2030-06-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04400084 on ClinicalTrials.gov