Atorvastatin as Adjunctive Therapy in COVID-19
NCT04380402 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2021-03-19
Summary
Objective: To assess whether adjunctive therapy of COVID-19 infection with atorvastatin reduces the deterioration in hospitalized patients and improves clinical outcome.
Conditions
Interventions
- DRUG
-
Atorvastatin 40 mg tablet
Sponsors & Collaborators
-
Mount Auburn Hospital
lead OTHER
Principal Investigators
-
Lin H Chen, MD · Mount Auburn Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-25
- Primary Completion
- 2021-12-31
- Completion
- 2022-05-08
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE)
NCT02099123 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to Atorvastatin
NCT00195793 ·Status: COMPLETED ·Phase: PHASE3
-
Self-Assessment Method for Statin Side-effects Or Nocebo
NCT02668016 ·Status: COMPLETED ·Phase: PHASE4
-
Patient Autonomy and Statin Therapy Adherence
NCT05845580 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Atorvastatin Treatment on Carotid Plaque.
NCT00343655 ·Status: TERMINATED ·Phase: PHASE3
-
A Study Of Pharmacokinetics, Pharmacodynamics And Safety Of Adding ETC-1002 To Atorvastatin 80 mg
NCT02659397 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial to Evaluate the Efficacy and Safety of CKD-391
NCT02451098 ·Status: COMPLETED ·Phase: PHASE3
-
Bioavailability Study for New Atorvastatin Formulation
NCT00844376 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Fenofibrate Added on to Atorvastatin Compared With Atorvastatin
NCT01956201 ·Status: UNKNOWN ·Phase: PHASE3
-
Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis
NCT00361283 ·Status: COMPLETED ·Phase: PHASE4
-
Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy
NCT04904536 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease
NCT00134264 ·Status: TERMINATED ·Phase: PHASE3
-
Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb Trial
NCT04466241 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Actual Use Trial of Atorvastatin Calcium 10 mg
NCT01964326 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Atorvo+™ in Healthy Adult Participants
NCT06615284 ·Status: COMPLETED ·Phase: PHASE1
-
Atorvastatin vs Colchicine in Decrease of Troponin I of High Sensitivity in Patients With Rheumatoid Arthritis.
NCT04056039 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Drug-Drug Interaction Between Enlicitide Decanoate (MK-0616) and Atorvastatin in Healthy Adult Participants (MK-0616-024)
NCT06699355 ·Status: COMPLETED ·Phase: PHASE1
-
VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome
NCT01130246 ·Status: TERMINATED ·Phase: PHASE3
-
Evaluate Safety and Efficacy of ABT-335 in Combination With Atorvastatin in Subjects With Multiple Abnormal Lipid Levels in the Blood
NCT00300469 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)
NCT01860729 ·Status: COMPLETED ·Phase: PHASE3
-
Statins for the Treatment of NASH
NCT04679376 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)
NCT00685776 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Trial to Evaluate the Efficacy of a Dyslipidemic Therapy in Mexican Population
NCT03696940 ·Status: UNKNOWN ·Phase: PHASE3
-
ATORvastatin in Pulmonary TUBerculosis: a POPulation PharmacoKinetics -PharmacoDynamics Sub-study (ATORTUB popPK-PD)
NCT07303699 ·Status: RECRUITING ·Phase: PHASE2
-
Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease
NCT00293748 ·Status: COMPLETED