Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients.
NCT04367779 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 84
Last updated 2026-04-22
Summary
This trial is a paucicentric, clinico-biological cohort study with retrospective and prospective enrollment, aiming to identify biomarkers predictive of response to Proton Beam Therapy (PBT) in cancer patients (high grade sarcoma, brain tumors and meningioma). This study include collection of clinical data, of tumor samples (collected during standard of care) and a blood sample for alive patients.
Conditions
- Brain Cancer
- Meningioma
- Sarcoma
Sponsors & Collaborators
-
Centre Leon Berard
lead OTHER
Principal Investigators
-
Claude Line · Centre Leon Berard
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-24
- Primary Completion
- 2024-09-05
- Completion
- 2024-09-05
Countries
- France
Study Locations
More Related Trials
-
Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors
NCT05313191 ·Status: RECRUITING ·Phase: NA
-
Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma
NCT04339218 ·Status: RECRUITING ·Phase: PHASE3
-
Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer
NCT04870840 ·Status: COMPLETED ·Phase: PHASE1
-
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
NCT05451004 ·Status: RECRUITING ·Phase: PHASE3
-
Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors
NCT05599048 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Prospective Evaluation of Stereotactic Body Radiotherapy for Metastatic Prostate Cancer
NCT02206724 ·Status: WITHDRAWN ·Phase: NA
-
Pencil Beam Scanning Proton Beam Radiotherapy for the Management of Abdominal Neuroblastoma
NCT06804447 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Immunological Function After Radiation With Either Proton or Photon Therapy
NCT06016699 ·Status: UNKNOWN
-
Simultaneous Integrated Boost in Carbon Ion Radiotherapy for Head and Neck Adenoid Cystic Carcinoma
NCT05733910 ·Status: RECRUITING ·Phase: NA
-
A Study of Mucosal Sparing Proton Beam Therapy (PBT) in Resected Oropharyngeal Tumors
NCT02736786 ·Status: COMPLETED
-
SMC Radiation Oncology SABR Cohort for Oligometastasis
NCT07121335 ·Status: RECRUITING
-
Using Breath, Cell Free DNA and Image Analysis to PRedIct Normal TissUe and Tumour Response During Prostate Cancer SBRT
NCT04081428 ·Status: ACTIVE_NOT_RECRUITING
-
Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer and Cholangiocarcinoma
NCT00976898 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Volumetric Radiotherapy in Prostate Cancer
NCT02423889 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer
NCT04342429 ·Status: RECRUITING ·Phase: NA
-
Investigating the Tumour Immune Response of Radiotherapy
NCT05076500 ·Status: RECRUITING
-
Proton Radiotherapy for Recurrent Tumors
NCT01126476 ·Status: COMPLETED ·Phase: NA
-
Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE
NCT04919226 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors
NCT06831461 ·Status: RECRUITING ·Phase: NA
-
Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema
NCT06837480 ·Status: RECRUITING ·Phase: NA
-
LITT and Pembrolizumab in Recurrent Brain Metastasis
NCT04187872 ·Status: TERMINATED ·Phase: PHASE1
-
Tumor Response in Hypofractionated Radiotherapy
NCT02854449 ·Status: UNKNOWN
-
Stereotactic Body Radio Therapy (SBRT) for Early-stage Non Small Cell Lung Cancer (NSCLC)
NCT00870116 ·Status: UNKNOWN ·Phase: NA
-
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
NCT05856773 ·Status: RECRUITING ·Phase: PHASE3
-
Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base
NCT05861245 ·Status: RECRUITING ·Phase: NA