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Biofreeze and the Effect on Knee Osteoarthritis

NCT04351594 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2024-12-04

No results posted yet for this study

Summary

Knee osteoarthritis (OA) is a progressive disease that can be accompanied by considerable joint pain and dysfunction. It is a goal in the medical field to find effective treatments for knee OA that are non-interventional, have minor or no negative side effects, and are relatively easy to administer for the patient and health care professionals. Biofreeze, a topical analgesic containing menthol, is an easily accessible gel, with no known serious negative side effects. If the application of Biofreeze can reduce the pain and dysfunction associated with knee OA, it could be an effective treatment for patients. The objective of the study is to assess how 4 weeks of Biofreeze application to a knee affected by OA effects pain and dysfunction associated with the disease.

Conditions

Interventions

DRUG

Biofreeze 4 % Topical Gel

Biofreeze gel with active manufactured ingredient (Menthol 4%)

OTHER

Biofreeze placebo gel

Biofreeze gel with no active manufactured to have the same look, feel and odour as Biofreeze topical gel.

Sponsors & Collaborators

  • Memorial University of Newfoundland

    lead OTHER

Principal Investigators

  • Nick Smith, MD (FRCSC) · Memorial University Orthopaedic Surgery

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-01
Primary Completion
2024-01-01
Completion
2024-01-01

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04351594 on ClinicalTrials.gov