Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma.
NCT04334499 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2023-03-23
Summary
This study is to characterize mitochondrial DNA (mtDNA) populations in adults with eye injuries and eye diseases. The eye exam is often hindered by the clouding of tissues involved in injury or disease. This protocol examines the use of mtDNA populations as indicators of developing inflammation and resolution of injury. This may be used to provide proactive treatment or define appropriate treatment needs beyond the indications of an ophthalmological exam.
Conditions
- Eye Diseases
- Ophthalmic Trauma
- Mitochondrial DNA
- Age Related Macular Degeneration
- Glaucoma
- Diabetic Retinopathy
Interventions
- OTHER
-
Sample collection from tissue discard
Collection of vitreous humor tissue and venous blood from subjects undergoing ocular surgery that may provide vitreous humor discarded tissue.
Sponsors & Collaborators
-
The University of Texas Medical Branch, Galveston
lead OTHER
Principal Investigators
-
Bartosz Szczesny, Ph.D. · University of Texas
Eligibility
- Min Age
- 20 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-02-21
- Primary Completion
- 2022-12-07
- Completion
- 2022-12-07
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