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Assessing Insulin Turnover Using an In-vivo Deuterated Water Experiment.

NCT04332289 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 4

Last updated 2020-10-01

No results posted yet for this study

Summary

The primary objective of this study is to observe the kinetics of pre-stored and de-novo synthesized insulin that is secreted into the circulation using an in-vivo heavy water (D2O) labelling experiment in patients with postprandial hyperinsulinaemic hypoglycaemia (PHH) and non-surgical non-PHH controls.

Conditions

Interventions

OTHER

Heavy water experiment

3 times daily heavy water (deuterated-water) and mixed meal administration for one week

Sponsors & Collaborators

  • Lia Bally

    lead OTHER

Principal Investigators

  • Lia Bally, MD, PhD · Bern University Hospital, University of Bern

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-07-09
Primary Completion
2020-08-13
Completion
2020-08-20

Countries

  • Switzerland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04332289 on ClinicalTrials.gov