Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial
NCT04324463 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 6667
Last updated 2024-01-11
Summary
ACT is a randomized clinical trial to assess therapies to reduce the clinical progression of COVID-19.
Conditions
- Coronavirus
- Severe Acute Respiratory Syndrome
Interventions
- DRUG
-
Colchicine
oral medication
- DRUG
-
Interferon-Beta
subcutaneous injection
- DRUG
-
oral medication
- DRUG
-
Rivaroxaban
oral medication
Sponsors & Collaborators
- collaborator INDUSTRY
-
Population Health Research Institute
lead OTHER
Principal Investigators
-
Richard Whitlock, MD PhD · Population Health Research Institute
-
Emilie Belley-Cote, MD PhD · Population Health Research Institute
-
John Eikelboom, MBBS MSc · Population Health Research Institute
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-21
- Primary Completion
- 2022-12-30
- Completion
- 2022-12-30
Countries
- Brazil
- Canada
- Colombia
- Ecuador
- Egypt
- India
- Nepal
- Pakistan
- Philippines
- Russia
- South Africa
- United Arab Emirates
Study Locations
More Related Trials
-
Stopping ACE-inhibitors in COVID-19
NCT04353596 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Collect Data on the Treatment Pattern of Xarelto + Acetylsalicylic Acid in the Routine Clinical Practice in Patients Who Are Suffering From a Condition That Narrows the Blood Vessels Supplying the Heart and / or a Condition That Most Commonly Narrows the Blood Vessel in the Legs
NCT04401761 ·Status: COMPLETED
-
FREEDOM COVID-19 Anticoagulation Strategy
NCT04512079 ·Status: COMPLETED ·Phase: PHASE4
-
Platelet Drug Trial in Coronary Disease Progression
NCT00000496 ·Status: COMPLETED ·Phase: PHASE3
-
CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19
NCT04516941 ·Status: TERMINATED ·Phase: PHASE3
-
Prevention of Complications (SARS-CoV-2): Clinical Study
NCT04788355 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation
NCT05797376 ·Status: COMPLETED ·Phase: PHASE4
-
Protective Effect of Aspirin on COVID-19 Patients
NCT04365309 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin
NCT03820466 ·Status: TERMINATED ·Phase: PHASE3
-
WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?
NCT04990791 ·Status: COMPLETED ·Phase: PHASE4
-
STAT-STatin and Aspirin in Trauma
NCT02901067 ·Status: TERMINATED ·Phase: PHASE2
-
Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI)
NCT00508924 ·Status: COMPLETED ·Phase: PHASE2
-
Platelet Function in Patients With an Acute Coronary Syndrome
NCT01992484 ·Status: UNKNOWN
-
Aspirin® Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis in Patients With PTS
NCT04128956 ·Status: TERMINATED ·Phase: PHASE2
-
To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome
NCT05573958 ·Status: UNKNOWN ·Phase: PHASE4
-
INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority
NCT02832544 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome
NCT02293395 ·Status: COMPLETED ·Phase: PHASE2
-
Acetylsalicylic Acid in the Prevention of Severe SARS-CoV2 Pneumonia in Hospitalised Patients With COVID-19
NCT04808895 ·Status: UNKNOWN ·Phase: PHASE3
-
EDUCATE: The MEDTRONIC Endeavor Drug Eluting Stenting: Understanding Care, Antiplatelet Agents and Thrombotic Events
NCT01069003 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Gain Insights in Treatment Patterns and Outcomes in Patients With Atherosclerosis Prescribed to Xarelto in Combination With Acetylsalicylic Acid
NCT03746275 ·Status: COMPLETED
-
Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome
NCT01952392 ·Status: COMPLETED
-
Study to Learn More About the Safety and Effectiveness of Rivaroxaban (Xarelto) When Given Together With Acetylsalicylic Acid to Indian People With Narrowing of the Arteries of the Heart (CAD) and/or With Reduced Blood Flow in the Arteries of the Legs and Arms With Symptoms (Symptomatic PAD)
NCT04298567 ·Status: COMPLETED
-
Aspirin Dose and Atherosclerosis in Patients With Heart Disease
NCT00272337 ·Status: COMPLETED ·Phase: PHASE4
-
HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)
NCT04801940 ·Status: UNKNOWN ·Phase: PHASE3
-
Predictors of Cardiovascular Risk in Covid-19 Patients During Acute Disease and at Short Term Follow-up
NCT04371289 ·Status: COMPLETED