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Effectiveness of Regenerative Endodontics Therapy for Single-rooted Mature Permanent Tooth With Pulp Necrosis

NCT04313010 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 346

Last updated 2020-03-23

No results posted yet for this study

Summary

This study is to evaluate the effectiveness of regenerative endodontics therapy in single-rooted permanent teeth with pulp necrosis，and compare the clinical efficacy of platelet rich fibrin (PRF) and blood clot (BC) as scaffolds.

Conditions

  • Pulp Necrosis

Interventions

OTHER

PRF

A sample of whole venous blood was drawn from the patient's forearm. The blood sample was transferred into a tube without anticoagulant and centrifuged immediately using a centrifuge.

OTHER

BC

According to the procedures of regenerative endodontics therapy, BC was made by the way of provoking apical bleeding into root canal.

Sponsors & Collaborators

  • Shenzhen Hospital, Southern Medical University

    collaborator UNKNOWN

  • Southern Medical University, China

    lead OTHER

Principal Investigators

  • Wanghong Zhao, Doctor · Nanfang Hospital, Southern Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
10 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-16
Primary Completion
2024-06-30
Completion
2024-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04313010 on ClinicalTrials.gov