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The Valsalva Urethral Profile : a Measure to Assess Stress Urinary Incontinence

NCT04311814 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 695

Last updated 2020-03-17

No results posted yet for this study

Summary

Clinical and paraclinical appraisal of stress urinary incontinence (SUI) is mainly based on the assessment of pelvic floor muscles (PFM) contraction and urethral mobility, the measurement of the maximum urethral closure pressure (MUCP) at rest by urethral pressure profilometry (UPP) and the measurement of the Valsalva leak point pressure (VLPP).

Currently, MUCP and VLPP cannot be used for diagnosing SUI because they appear to be moderately correlated with the severity of SUI.

The lack of a specific SUI biomarker could be the explanation for the poor predictive value of urodynamics and the ongoing debate on whether urodynamic testing before surgery has benefits. Our main objective was to study the value of a new urodynamic parameter in the diagnosis of female SUI: the Valsalva urethral profile (VUP)

Conditions

  • Stress Urinary Incontinence

Interventions

DIAGNOSTIC_TEST

Maximum urethral closure pressure during Valsalva (v-MUCP)

v-MUCP measurement was performed for all patients referred for urodynamic exploration of the lower urinary tract

Sponsors & Collaborators

  • Poissy-Saint Germain Hospital

    lead OTHER

Principal Investigators

  • Philippe Dompeyre, MD · Intercommunal Hsopital center of Poissy Saint Germain

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-02-15
Primary Completion
2019-09-25
Completion
2019-12-20

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04311814 on ClinicalTrials.gov