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Natural Cycle Versus Hormone Replaced Cycle

NCT04310683 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2026-08-24

No results posted yet for this study

Summary

Recent sutdies indicate that the existence of corpus lutein in the ovary is a key point to prevent preeclampsia, and patients undergoing FET with hormone replaced cycle have no corpus lutein and the absence of corpus lutein significantly increases the risk of preeclampsia in these patients. We aim to conduct a single center randomized controlled non-inferiority trial to compare the live birth rate and gestational hypertention disease rate between the natural cycle and the hormone replaced cycle in women undergoing FET.

Conditions

  • IVF

Interventions

PROCEDURE

natural cycle for endometrium preparation

patients will not use oral contraceptive drugs

PROCEDURE

hormone replaced cycle for endometrium preparation

patients will receive oral contraceptive drugs for menstruation before embryo transfer

Sponsors & Collaborators

  • Women's Hospital School Of Medicine Zhejiang University

    lead OTHER

Principal Investigators

  • Dan Zhang, M.D. Ph.D. · Women's Hospital School Of Medicine Zhejiang University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-10
Primary Completion
2020-12-10
Completion
2020-12-10

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04310683 on ClinicalTrials.gov